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Adaptation stage: Each mouse was put into the experimental device and left to explore freely for 5 min to adapt

The goal of the therapy is to create negative pressure within the disc, which can help to alleviate pain and promote healing

We performed electrochemical HPLC analysis to determine the GSH concentration of 24 skeletal muscle biopsies from patients with defined ETC defects compared to 15 age-matched disease controls

Variables that regulate cellular respiration, including NAD-related substrates, oxygen, succinate, and antioxidant enzymes, modulate ROS levels and sustain cellular redox equilibrium

During strenuous exercise, illness, or exposure to heat, these electrolytes can be lost through sweating