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This expansion was accompanied by an upregulation of the cytokines interleukin-2 (IL-2), interleukin-4 (IL-4), and interleukin-10 (IL-10) in colonic tissues

Several are also prohibited in competitive sport

Table 3 Aptamers for solid tumor immunotherapy in clinical trials that are currently active

In other cases, the regulatory Zn II coordination site may be at or very near the protein surface where it functions at a distance as an allosteric modulator of protein function