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Pharmacological treatment of the overweight patient

In clinical trials, adults who used Wegovy alongside diet and lifestyle changes lost an average of 1415% of their body weight over one year.* Individual results vary based on factors such as dosage, adherence, lifestyle habits, and overall health

These findings establish the mechanistic basis for the compound and provide proof of concept for its metabolic effects

By inhibiting NNMT, the compound shifts cellular metabolism away from fat storage and toward fat burning

At the molecular level, it modulates the expression of over 4,000 human genes, roughly 6% of the genome, according to a 2012 Broad Institute Connectivity Map analysis published by Pickart, Campbell, and colleagues