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Moreover, adjunctive therapies such as prebiotics, probiotics, and postbiotics are also used to manage oxidative stress and help treat IBD

Vitamin C and glutathione work synergistically vitamin C regenerates oxidised glutathione back to its active form, and glutathione recycles oxidised vitamin C

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Therefore, besides citrate-derived acetyl-CoA by nuclear ATP-citrate lyase 68 , the carnitine-mediated supply of acetyl groups is also an important source of acetyl-CoA for nuclear histone acetylation