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Between 2011/12 and 2022/23 daily smoking reduced from 16.4% to 6.8%

RA therefore can be divided into two subsets of disease entities (ACPA-positive RA and ACPA-negative RA), which are likely to be genetically distinct: HLA-DRB1 SE alleles and PTPN22 are restricted to ACPA-positive RA, while genes such as interferon regulatory factor 5 (IRF-5) and C-type lectin seem to confer risk for ACPA-negative RA [26]

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We have so many examples of people turning their lives around completely after quitting smoking with support from the Wellbeing Team, and you only have to look at the figures released today to see what a positive impact that could have for everyone. Diane Lee, NELC Director of Public Health, said: The need for action is clear, tobacco cannot be allowed to continue taking lives, money, and services from our communities

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