10.1002/ana.410070403 56 PlaitakisA.ShashidharanP
DPP-4i could restore the inactivation of AKT and ERK signaling and inhibit NF-B activation to reduce the production of pro-inflammatory factors, including TNF-, IL-1, monocyte chemoattractant protein-1 (MCP-1), ICAM-1 and TGF- (169, 170)
We believe that bioavailable nutraceuticals are the foundation of optimal treatment outcomes as well as an invaluable part of preventive care
Moreover, radical-scavenging antioxidants such as Astragenol, Acteoside, and Edaravone have demonstrated neuroprotective effects in NDDs, primarily by neutralizing ROS, promoting GSH synthesis, and maintaining GPX4 activity to alleviate neuronal ferroptosis (Xiao et al., 2025
This oil is rich in fatty acids, including: two types of linoleic acid (~30-34%), oleic acid (17%), and palmiteic acid (35%)