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Tbeta4 was used to treat N20.1 cells (premature oligodendrocyte cell line) in vitro, and the proliferation of N20.1 cells was measured by bromodeoxyuridine (BrdU) immunostaining

The method of any one of embodiments 39-42, wherein the medium chain fatty acids are caproic acid (hexanoic acid), enanthic acid (heptanoic acid), caprylic acid (octanoic acid), pelargonic acid (nonanoic acid), capric acid (decanoic acid), undecylenic acid (undec-10-enoic acid), lauric acid (dodecanoic acid), or any combinations thereof

Wacharasint P, Boyd JH, Russell JA, Walley KR

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NICE guidance on the assessment and management of overweight and obesity in adults (currently CG189 and associated updates) provides the overarching framework, alongside the technology appraisals for semaglutide 2