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GLP1: glucagon- like peptide1) Serotonin (5- hydroxytryptamine or 5HT) receptor modulation The nonselective serotonergic antiobesity drugs fenfluramine and dexfenfluramine have been associated with severe side effects like valvular heart disease and pulmonary hypertension

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Providers routinely encounter patients who experience severe gastrointestinal intolerance, metabolic adaptation, or frustrating weight loss plateaus that render these first-line therapies insufficient

Available from: Jett, L., Lger, R., Thibaudeau, K., Benquet, C., Robitaille, M., Pellerin, I., Paradis, V., van Wyk, P., Pham, K., & Bridon, D