Hydrolysis of Cysteinylglycine and Its Conjugates At least four peptidases/dipeptidases have been identified to cleave cysteinylglycine and its conjugates, including membrane-bound (aminopeptidase N and cysteinylglycine dipeptidase) and cytosolic (a nonspecific enzyme and leucyl aminopeptidase/prolyl aminopeptidase) enzymes (Poon and Josephy, 2012 and references cited therein)
Clinical evidence: What studies actually show Separating proven benefits from theoretical applications requires examining research quality
Sobhani I, Itti E, Luciani A, Baumgaertner I, Layese R, Andre T, et al
The ideal would therefore be to provide large amounts of glycine (5 to 10 g per day) and moderate amounts of acetylcysteine (200 to 400 mg per day)
Main Therapy resistance is a major clinical problem, limiting the effectiveness of cancer treatments