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The closest comparison is with AHK-Cu (Ala-His-Lys with copper), a related copper-binding tripeptide that shares the histidine-anchored coordination chemistry but has alanine rather than glycine at position 1

The review synthesized findings from cell-culture experiments (human dermal fibroblasts, keratinocytes, irradiated fibroblasts), animal models (rats, mice, pigs, dogs), and human cosmetic-science studies of topical formulations

This guide covers everything researchers need to know when GHK-CU appears to be making skin worse

Quick Comparison Molecular class: AOD-9604 is a synthetic HGH fragment (16 amino acids)

Data are mean SEM, n = 8/group