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What Happens During a B12 Injection Appointment Blood tests are generally needed to confirm B12 deficiency before starting injections, since guessing at a deficiency without lab work risks over-treating a problem that isnt actually present

Most people barely feel it with small insulin needles

Summary: B12 deficiency may be caused by malabsorption, poor dietary intake and/or pernicious anemia

Because the body cannot produce B12 independently, deficiency develops when dietary intake is inadequate or absorption is impaired

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