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The studies have suggested that in comparison with rodents, relatively little AFB1-GSH conjugate is produced by human liver, but insufficient data exist to be certain that this reaction is not of physiological importance in man, particularly as an aflatoxin mercapturate has been detected in the urine of marmoset monkeys treated with AFB 1

Further investigation showed that exposure of RAW264.7 cells to recombinant IFN-I, including IFN- and IFN-, activated the STAT-1 signaling pathway via phosphorylation of JAK1 and tyrosine kinase 2 (TYK2)

Green R, Allen LH, Bjrke-Monsen AL, et al

Therefore, we can detect only indicators associated with ferroptosis as much as possible

The expression of CD14, TLR2 and 4 in human alveolar type I and II cells (Thorley et al., 2011) suggests that they most probably participate in SARS-CoV-2 infection and COVID-19 disease