doi:10.1038/s41598-026-37537-4 CrossRef Abbreviation AGEs Advanced Glycation End Products AP-1 Activator Protein-1 CAT Catalase COX-2 Cyclooxygenase-2 ECM Extracellular Matrix FGF Fibroblast Growth Factor GSH Reduced Glutathione HPLC High-Performance Liquid Chromatography IL-1 Interleukin-1 Beta IL-6 Interleukin-6 iNOS Inducible Nitric Oxide Synthase Keap1 Kelch-like ECH -associated Protein 1 LC-MS Liquid ChromatographyMass Spectrometry MDA Malondialdehyde MMPs Matrix Metalloproteinases NADPH Nicotinamide Adenine Dinucleotide Phosphate NF-B Nuclear Factor Kappa B NMR Nuclear Magnetic Resonance Nrf2 Nuclear Factor Erythroid 2Related Factor 2 PDGF Platelet-Derived Growth Factor ROS Reactive Oxygen Species SOD Superoxide Dismutase STZ Streptozotocin TGF- Transforming Growth Factor Beta TNF- Tumour Necrosis Factor Alpha VEGF Vascular Endothelial Growth Factor Received on: 02-03-2026 Accepted on: 25-03-2026 Reviewed by: Dr
Mast cell activation causes either neuroprotection or neuroinflammation based upon the level and number of cells activated (Mukai et al., 2016)
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525,526 Huntingtons disease (HD) HD, also known as Huntingtons chorea (Huntingtons chorea), is an autosomal dominant hereditary neurodegenerative disorder that has a tremendous devastating effect on patients and their families, characterized by chorea-like movements, cognitive decline and psychotic-like symptoms
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