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Understanding their synergy allows physicians to tailor therapy based on injury type, tissue depth, and overall health goals
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In addition, the oldest orphan nuclear receptor estrogen-related receptor (ERR), an important regulator of metabolic gene transcription and innate immune function, including those induced by toll-like receptor (TLR) and antimicrobial activities against intracellular bacterial infection [147], facilitated post-translational activation of autophagy by deacetylating various autophagy-related proteins, including ATG5, BECN1, and ATG7
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