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Various subcortical networks communicate with the mPFC, including the amygdala (responsible for emotional processing), the NAc (responsible for social incentive), and the hypothalamus (responsible for stress regulation)

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While the mechanism is not fully understood, BPC-157 appears to influence dopamine and serotonin systems in ways that may counteract some of the mood changes that occasionally accompany significant dietary restriction

[DOI] [PubMed] [Google Scholar] 156.Poderoso J.J., Carreras M.C., Lisdero C., Riobo N., Schopfer F., Boveris A