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Given the biphasic dose-response curve described above for cardiovascular effects, a reconstitution error that doubles the intended dose may shift the patient from a vasodilatory to a vasopressor pharmacodynamic regime

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Nevertheless, astrocytes and other glia can also mediate detrimental effects in neurological disorders either through downregulation of essential functions or through gain of inappropriate functions such as promoting excess inflammation

Psychiatry 7 , e1137 (2017) PubMed