Moreover, the gut microbiota and its associated metabolites promote the differentiation and function of anti-inflammatory macrophages, Treg cells, CD4 + CD8 + regulatory cells, IL-10 + and/or IL-35 + B regulatory cells, as well as IL-22-producing innate lymphoid cells 3 (ILC3), which are involved in maintaining the gut mucosal homeostasis (Su et al., 2022) and protecting the kidneys (Su et al., 2022)
J Am Coll Nutr 37(8):738748 Kuo YT et al (2015) Pyrroloquinoline quinone resists denervation-induced skeletal muscle atrophy by activating PGC-1alpha and integrating mitochondrial electron transport chain complexes
The term organic component as used hereinafter refers to mixtures comprising said phospholipid, lipophilic additives and organic solvents
Importantly, food intake remained unchanged in treated animals, suggesting the compound's effects relate to energy expenditure pathways rather than appetite
WangXXEdelsteinMHGafterUQiuLLuoYDobrinskikhEet al