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Non-pharmacological interventions and management for ME/CFS Cognitive behavioral therapy (CBT) Grounded in the biopsychosocial model, CBT facilitates the targeted modification of dysfunctional beliefs, avoidance behaviors, and maladaptive coping strategies [159]

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[87] [88] In plants, the extracellular nicotinamide adenine dinucleotide induces resistance to pathogen infection and the first extracellular NAD receptor has been identified

NAD+ is involved in all three stages of cellular respiration: glycolysis, the citric acid cycle, and oxidative phosphorylation, leading to the production of ATP

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