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In order to gain insights into biological pathways associated with increasing emphysema severity within a patient and explore computational strategies for identifying COPD therapeutics, we obtained paired samples from eight regions at regular intervals between the apex and base of each explanted lung from six patients with severe COPD (Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage IV) and two donor lungs

10.1016/j.jaci.2010.01.051 13

Improvement of stem cell-derived exosome release efficiency by surface-modified nanoparticles

It demands more from us as researchersmore precision, more planning, and a deeper appreciation for the elegant, fleeting dance of biochemistry

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