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Glutathione (GSH) is a tripeptide molecule made from three amino acids: Cysteine (rate-limiting amino acid-contains sulfur) Glycine Glutamate It exists in two forms: Reduced glutathione (GSH) : Active form, the antioxidant Oxidized glutathione (GSSG) : Inactive form, created when GSH neutralizes free radicals The GSH:GSSG ratio is a critical marker of oxidative stress

10.1016/j.vetimm.2004.12.007

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It remains a reference compound in studies examining neuropeptide transport, stress-axis neuromodulation, and circadian rhythm biochemistry