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Symptoms of B12 deficiency can appear in years because the body naturally stores the vitamin in the liver

This improves patient results

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Common clinical drivers include: Vitamin B12 deficiency Folate deficiency Chronic liver disease Alcohol use disorder Medications (e.g., methotrexate) Bone marrow disorders Chronic inflammatory disease Hypothyroidism Key ICD-10 principle: Cell size is a laboratory observation

This irritation can interfere with the body's ability to take in enough vitamin B12 from food or supplements