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The protein expression of TIMP-1 was decreased in the CS group when compared with the control group, whereas pretreatment with medium and high dosages of GHK-Cu increased it when compared to the CS group (Figures 2B,D)

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i.p.), pupils were dilated with tropicamide (Mydriacyl 1% Alcon, United Kingdom) two drops in both eyes, and then anesthetized with tetracaine drops (Tetracaine, Pliva, Zagreb, Croatia) in both eyes

Versus microneedling alone Microneedling is a delivery and remodeling method rather than a brightening agent by itself