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Am J Clin Nutr 89:2025S-2039S

Similarly, examining how acute and/or repeated applications of neuropeptides affect expression of mucins (e.g., muc5AC, muc5B) in asthma, COPD, and CF would reveal a potentially causative role for neuropeptides in airway mucus phenotypes

With respect to hypertension, several in vivo studies have provided evidence that eNOS uncoupling occurs in animal models of increased blood pressure, including ATII hypertension, 14 DOCA-salt induced hypertension, 57 NOX1 upregulation 83 and genetically determined hypertension 84 in which an uncoupled eNOS was consistently identified as a significant superoxide source

In vitro testing confirmed that MSU crystals trigger the manifestation of macrophage rs45520937 and amplify the expression of NLRP3 and IL-1 (44)

Nine of the 15 differential metabolic pathways were regulated by XJZ-A