Results: Treatment with NTZ lessened the serum liver enzymes, reduced malondialdehyde (lipid peroxidation product), enhanced antioxidant capacity, attenuated proinflammatory cytokines, and suppressed apoptosis
DAO is an enzyme found in the gut that metabolizes histamine in the GI tract, which can be a significant source of histamine, especially in the presence of SIBO, candida overgrowth and certain pathogenic infections like Kl and ebsiella spp
reported that BPC-157 administered intraperitoneally to rats at doses of 10 mg/kg and above produced no mortality, no observable organ damage on histopathology, and no significant changes in hematologic or hepatic panels 1
& Eisenman, R
A previous study showed distinct serum metabolomic signatures between AHU and gout, and arginine metabolism seems to play a crucial role [18], which were consistent with our finding from pathway analysis