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On the cell membrane, the cystine/glutamate antiporter SLC7A11/SLC3A2also known as system Xc transports extracellular cystine into the cell in a 1:1 exchange with intracellular glutamate release (101)

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After incubation, cells were gently resuspended, stained with CD11b-BV421 (LM2, 393114, BioLegend, USA) for 30 minutes, washed with PBS, and analyzed by flow cytometry to assess tumor cell phagocytosis

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Temperature fluctuations degrade the peptide structure [12][15]