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If you intend to supplement vitamin B12, choose a form with methylcobalamin, hydroxocobalamin, adenosylcobalamin, or a combination of these (avoid cyanocobalamin, if possible)

WADA Classification: May be listed as a prohibited substance by the World Anti-Doping Agency (WADA)

Key Preclinical Study (Neelakantan et al., 2018): Treatment in diet-induced obese mice produced progressive body weight loss, reduced white adipose tissue mass and adipocyte size, decreased total cholesterol, and no changes in food intake effects were metabolic, not appetite-driven

But clinical data, dosing, and understanding of the broader effects in humans lacks study

Community estimates suggest that source quality explains approximately 80% of the variation in user outcomes