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Even though many tumors overexpress GST P1-1 11, 35, 36 it is not obvious that the elevation is sufficient to compensate for the relatively low activity of this enzyme in comparison with other GSTs and make the neoplastic cells selectively vulnerable to release of NO from JS-K

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Despite its availability in food, some individuals struggle to maintain sufficient B12 levels due to dietary restrictions, medical conditions, or absorption issues

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