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It is, however, a biologically coherent mechanism that warrants extreme caution

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Its role in regulating lower esophageal sphincter function through interaction with smooth muscle receptors provides theoretical rationale for combination with BPC-157

10.1167/tvst.8.4.23 75 VukojevicJ.SiroglavicM.KasnikK.KraljT.StancicD.KokotA.et al (2018)

Clinical Update 5/31/2024 Coffee Intake & Osteoporosis Drinking coffee was linked with a lower risk of osteoporosis in a recent study, but the amount and type of coffee both appear to matter