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Although in vitro assays are not able to replace all conventional animal bioassays, they are increasingly seen as alternatives to animal testing of drugs and chemicals, in the European Union, the United States, and elsewhere (Hfer et al

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Those who insist they are 95% less dangerous are therefore only making fingers-crossed predictions, much in the same way that the scientific colossus Ernst Wynder (who published the first case control study on smoking and lung cancer) did about his hopes for reduced-risk cigarettes

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In an industry where thinness is highly valued, cigarettes might be used as appetite-suppressants, she adds