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Evidence suggests that OS is a common signature in neurodegenerative diseases such as Alzheimers disease (AD) [47,48,49], Huntingtons disease (HD) [50,51,52], Parkinsons disease (PD) [53,54,55] and, in particular, it is part of the tightly connected and multi-factorial set of mechanisms involved in the pathogenesis and progression of Amyotrophic lateral sclerosis (ALS) [25, 56,57,58]

Epithelial-immune cell interplay in primary sjogren syndrome salivary gland pathogenesis

Ischemia reduces the supply of oxygen and nutrients to brain tissue, triggering OS and inflammation, directly or indirectly influencing metal ion metabolism, including iron ions (82, 83)

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