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Tail vein (165, 166), hepatic vein (167) and peripheral vein (168) injection of MSCs in an ischaemia-reperfusion injury animal model showed that MSC infusion can reduce liver damage and cell death (165, 167), improve the levels of ALT and AST (166168) and mainly decrease oxidative stress caused by liver excision and ischaemia-reperfusion injury (169)

The limit of 100 conformers was chosen as this is considered to be a standard number of conformers to be used in molecular modelling analyses and to balance computational time requirements whilst ensuring the production of an appropriate ensemble size [29]

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Human studies mainly used short-term intravenous DSIP injections under controlled research conditions, typically at 25 nmol/kg, but these studies were small, short-duration, and not designed to establish long-term safety or optimal dosing

The neutral pH of the colonized niche causes dormant H