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The CagriSema amylin+GLP-1 combination achieves effects comparable to Retatrutide monotherapy, but Retatrutide has a stronger standalone effect (24 % in Phase 2)

Our study also suggests that upregulating the expression of DDIT4 in target cells and organs could serve as a strategy to improve AMSC therapeutic potency, which establish a theoretical foundation for the further development of stem cell-based alternative therapies

POINTER components, refer to Figure 20

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