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The diagnosis of adult-onset Stills disease (AOSD) was based on the Yamaguchi criteria, after exclusion of infectious, hematologic, and autoimmune diseases

This finding is in accordance with a previous study showing that adjuvant alone was not sufficient to initiate mucosal inflammation 39

Discomfort, pain, bruising, inflammation, injury, and numbness at the site of injection

Advancements in ROS imaging, such as bioluminescent sensors, protein-based reporters, and hybrid modalities like PET-ROS imaging, are emerging but remain limited by sensitivity, specificity, and tissue accessibility (Hawkins and Davies, 2019