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The GHRH (Tesamorelin) tells the pituitary to release its stored growth hormone, while the GHRP (Ipamorelin) amplifies that signal and reduces the inhibition

Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias

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However the down side to this increased mitochondrial function was that more oxidative damage occurred (3) , so the researchers decided to add the powerful mitochondrial antioxidant alpha lipoic acid (ALA) to the mix to see if they could get the best of both worlds: increased mitochondrial energy output, with reduced mitochondrial damage