Class A G-protein-coupled receptor (GPCR) dimers and bivalent ligands
Carbon dots, thanks to their abilities to penetrate the BBB and the excellent photoluminescence may represent promising nanocarriers for drug delivery in neural compartments and for potential use as AD therapy, by inhibiting oxidative stress, neurotoxicity as well as for restoring nerve damage and maintaining neuronal morphology according to the released payload (Kuang et al., 2020
SFRP1 (secreted frizzled-related protein 1) promoter DNA hypermethylation reduces the mRNA expression levels of SFRP1 , and it is regulated by H3K27me3 and DNA methylation (Wu et al., 2023)
It may also have potential benefits to immune system health, and plays a role in amino acid transport across membranes and protein synthesis
Study 2: The Effect of GlyNAC Supplementation on Key Age-Associated Defects in the Heart, Liver and Kidneys This separate and parallel study was conducted to investigate mechanisms which could have contributed to longevity as a result of GlyNAC supplementation