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Chronic stress dysregulates this axis, leading to elevated cortisol, poor stress recovery, and constant anxiety

One particularly attractive but mostly overlooked neurotrophic factor is HGF, which has a proven ability to both stimulate neurogenesis (Shang et al., 2011, Wang et al, 2011) and synaptogenesis (see preliminary studies below)

The contribution of GHK versus 5-ALA to the observed effect cannot be isolated from this trial alone

Emerging Fields: Researchers are now exploring their potential in non-alcoholic fatty liver disease (NAFLD), addiction (by modulating the brain's reward pathways), and even neurodegenerative diseases like Alzheimer's and Parkinson's, likely through anti-inflammatory and metabolic effects within the brain

Dissociated hippocampal neurons were treated with H2O2 for 24hrs +/- HGF at sub-threshold concentrations 5ng/ml and or Dihexa at 2 different concentrations 10 "8 M and 10 "8 M