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This dosage is typically the highest strength available and is intended for individuals with a higher level of nicotine dependence

Exclusion criteria were simultaneous use of any other nicotine or tobacco product (including cigarettes, e-cigarettes, and nicotine replacement therapy), drug use (including cannabis), alcohol dependence, eating disorder, and current or planned pregnancy

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Local colonial governments occasionally took specific measures against cannabis, such as British East Africa (an area of present-day Kenya, Uganda and Tanzania), which banned it in 1914 as the war began

Consistently, for over 25 years, cigarettes butts have been the top item collected during the International Coastal Cleanup (ICC)