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[2] Broader reviews position the peptide as producing an angiogenic, healing-promoting effect across gastrointestinal and extra-gastrointestinal tissues, tying its action to the nitric-oxide system and to standard angiogenic growth factors

doi: 10.3389/frph.2022.822257 Received 25 November 2021 Accepted 17 January 2022 Published 22 February 2022 Volume 4 - 2022 Edited by Roland Eghoghosoa Akhigbe, Ladoke Akintola University of Technology, Nigeria Reviewed by Giulia Collodel, University of Siena, Italy