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The solution here was vaginal administration of THC (the active component of marijuana) to the mice (how would you like that job :-).[ref] Mast cells and rheumatoid arthritis: Rheumatoid arthritis is an autoimmune disease that causes painful inflammation of the joints

Lucey MR, Terrault N, Ojo L, Hay JE, Neuberger J, Blumberg E, et al

Poor sleep further impairs emotional regulation, decision-making, and impulse control, increasing vulnerability to relapse during early recovery

An implication therefore was that NPY might contribute to diseases like COPD and asthma, in which elevated interleukin 6 has been found in the sputum [187]

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