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japonicum GST (~40 units/mg), glutathione, tannic acid, cibacron blue, hematin, ethacrynic acid, 1,2-dichloro-4-nitrobenzene (DCNB) and 2,4-dinitrochlorobenzene (CDNB) were from Sigma-Aldrich Co

First, our study was a single-arm study without a control group

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To examine whether GSH depletion causes SIPS in RPE cells, we first analyzed cell cycle by flow cytometry