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GCLC knockout mice die within a month of birth due to the absence of hepatic GSH synthesis

Therefore, 5-[(3S,8R,9S,10R,13R,14S,17R)-14-hydroxy-10,13-dimethyl-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-1,2,3,6,7,8,9,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]pyran-2-one (9) with lower binding affinity value, which indicate better inhibitory activities, was reconnoitered for ADMET study via ADMETlab ( an online ADMET software

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The isomers, aloe-emodin and emodin, possess differential inhibitory activities against CYP1B1 enzyme

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