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I will say, despite the fact that the cispeptin pathway is well known, and despite the fact that the cispeptin peptide is designed to mimic a naturally occurring peptide that has a pretty constrained set of functions, in the hypothalamic pituitary system

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Sittl R, Lampert A, Huth T et al (2012) Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype NaV1.6-resurgent and persistent current