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Full normalization of endocrine, hepatic, and lipid profiles can take several months post-cycle, even with proper PCT. Kanayama, Current Opinion in Endocrinology, Diabetes and Obesity 2

However, they work only while you take them, do nothing to promote tissue repair, and carry risks of gastrointestinal, cardiovascular, and renal side effects with prolonged use

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The p53 mediates apoptosis by inducing the release of mitochondria cytochrome c with subsequent caspase activation along with the cleavage of caspase substrates