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Consuming ALA on an empty stomach (under acidic pH) optimizes gastric mucosal absorption [10], whereas food intake reduces bioavailability due to delayed gastric emptying and interactions with dietary components [11]

It has been claimed also that aqueous extract have anti-inflammatory (McKoy et al., 2002) and antioxidative activities (Ikeda et al., 2009) in several in vitro test systems

10.1186/s40824-022-00276-4 Biomater

However, body composition outcomes favor the stack

Current literature suggests subclinical cardiovascular damage from cardiac antigen exposure during prior lines of therapy may be amplified with subsequent immunotherapy resulting in cardiac toxicity