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In these models an increased expression of lactate transporters across the bloodbrain barrier was observed compared to controls, indicating that the brain can compensate for intrinsic deficits by using other bodily sources

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Bone morphogenetic proteins (BMPs) secreted by lung resident cells can restrict cancer development by turning cancer cells into a dormant state, while Coco and GALNTs derived from lung metastatic breast tumor cells are able to inhibit the effect of BMPs and reactivate dormant tumor cells to seed in the lung, thereby leading to metastasis (117)

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10.3389/fpls.2016.01109 110 McGoldrickS.O'SullivanS