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However, a 6-month RCT funded by Kyowa Hakko (n=54) found that taking 250 mg or 1,000 mg of Setria glutathione daily for 6 months significantly increased glutathione levels in blood, buccal cells, and erythrocytes, with the higher dose producing greater increases

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The pro-apoptotic protein p53 can be degraded through the exosome miR-769-5p-mediated ubiquitin-proteasome pathway, ultimately leading to cisplatin resistance (31)

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