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Absolute contraindications include personal or family history of medullary thyroid carcinoma (MTC), Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), previous serious hypersensitivity to semaglutide or formulation components, pregnancy (the medication should be discontinued at least 2 months before planned conception), and breastfeeding due to insufficient data on excretion in human milk

J Neurosci Methods 2018;297:18

Ramirez, F., Dundar, F., Diehl, S., Gruning, B

Rigorous LC-MS characterisation across doses and routes would provide a more definitive reference

De Graauw, M., Le Dvdec, S., Tijdens, I., Smeets, M.J., Deelder, A.M