Additionally, laboratories may evaluate multiple compounds within the same category to better understand formulation consistency, preparation considerations, and analytical performance
Seiwerth S, Milavic M, Vukojevic J, Gojkovic S, Krezic I, Vuletic LB, Pavlov KH, Petrovic A, Sikiric S, Vranes H, Prtoric A, Zizek H, Durasin T, Dobric I, Staresinic M, Strbe S, Knezevic M, Sola M, Kokot A, Sever M, Lovric E, Skrtic A, Blagaic AB, Sikiric P
Studies examining multi-dose vial sterility have documented that preservative-containing diluents maintain vial integrity through the labeled use period (PMID: 6562087)
doi:10.1016/j.burns.2014.06.001
Each step up delivered approximately 3 additional percentage points of weight loss, suggesting the compound was still climbing toward its ceiling at the highest dose