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However, the arcuate nucleus (ARC) of the hypothalamus showed increased glucose uptake only in BAT after leptin injection, while other nuclei like the dorsomedial hypothalamus (DMH) or the paraventricular hypothalamus (PVH) had no effect on glucose uptake when injected with leptin or Melatonan 2

In some of these patients, the stimulation was also associated with psychologic improvements, such as reductions of anxiety or improved visuomotor functions [128, 140, 148]