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These receptors are expressed in various tissues and cells, enabling VIP to exert its pleiotropic effects

Mt Sinai J Med 77:3242

Am J Psychiatry 1991

methylcobalamin is an active form of B12 alone or in combos

Reconstitution: Add 2.0 mL bacteriostatic water 5 mg/mL Typical Dose Range: 250500 mcg daily Measurement: 1 unit (U-100 syringe) = ~50 mcg Storage: Lyophilized: 20C Reconstituted: 28C (use within 12 weeks) Dosing & Reconstitution Guide Educational guide for reconstitution and daily dosing Standard / Gradual Titration (2 mL = 5 mg/mL) Maintenance (After Week 8): 250 mcg 2-3 weekly (5 units) Administer via subcutaneous injection once daily during the initial 8-week tanning phase , then transition to 2-3 injections per week for maintenance to help sustain pigmentation